{"id":1152410,"date":"2024-10-10T08:37:21","date_gmt":"2024-10-10T12:37:21","guid":{"rendered":"https:\/\/nortonhealthcare.com\/?post_type=service&#038;p=1152410"},"modified":"2024-10-10T09:25:24","modified_gmt":"2024-10-10T13:25:24","slug":"treatments","status":"publish","type":"service","link":"https:\/\/nortonhealthcare.com\/services-and-conditions\/cancer-care\/services\/ovarian-cancer\/treatments\/","title":{"rendered":"Ovarian Cancer Treatment Options"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/nortonhealthcare.com\/services-and-conditions\/cancer-care\/services\/ovarian-cancer\/\">Ovarian cancer<\/a> treatment options depend on how far your cancer has progressed \u2014 the stage \u2014 and the nature, or grade, of tumor cells.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Epithelial ovarian cancer is the most common form of the disease. It is characterized by cancer cells developing in the exterior lining of the ovary, or epithelia.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The first approach for treatment in nearly all instances of epithelial ovarian cancer is surgical removal of one or both ovaries and tumors. If the cancer has spread to other organs, surgery would be more aggressive. After surgery, the next course of treatment is typically chemotherapy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The regimen of surgery and chemotherapy erases evidence of cancer in imaging scans and blood tests about 80% of the time. Sometimes more aggressive measures are needed to achieve a full response to treatment or address any recurrence.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The outlook for recovery depends on the type of ovarian cancer, how far it\u2019s progressed and the effectiveness of treatment. In cases when diagnosis is made before any cancer cells spread to nearby tissue, about 92% of patients survive five years and longer. Overall, the five-year survival rate for epithelial ovarian cancer is about 51%.<\/p>\n\n\n<div class=\"card card-callout  mx-auto w-xl-50 \">\n\t<div class=\"card-body\">\n\t\t\n\n<h2 class=\"has-text-align-center wp-block-heading\" id=\"h-at-the-forefront-of-ovarian-cancer-care\">At the Forefront of Ovarian Cancer Care<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/nortonhealthcare.com\/services-and-conditions\/cancer-care\/\">Norton Cancer Institute<\/a> uses advanced testing options to help your specialist determine a care plan and tailor it for you. Our gynecologic specialists will coordinate your care with surgical oncologists, medical oncologists and, if appropriate, radiation oncologists.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Norton Cancer Institute <a href=\"https:\/\/providers.nortonhealthcare.com\/search?specialties=Gynecologic%20Oncology&amp;sort=networks%2Crelevance&amp;search_alerts=false&amp;shuffle_seed=d8bba113-0611-4c96-b15c-afeefcc34882&amp;provider_fields=-clinical_keywords&amp;filter=provider.provider_is_employed%3Atrue\">gynecologic oncologists<\/a> are also researchers. As principal investigators in a number of <a href=\"https:\/\/nortonhealthcare.com\/services-and-conditions\/cancer-care\/services\/cervical-cancer\/clinical-trials\/\">clinical trials<\/a> that could offer innovative approaches, they can provide patients easier access to appropriate trials. Once experimental treatments are approved for wide use, Norton Cancer Institute oncologists often have years of experience with the therapy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The <a href=\"https:\/\/nortonhealthcare.com\/news\/on-site-genomic-testing-at-norton-cancer-institute-allows-fast-and-precise-treatment\/\">Norton Cancer Institute Genomics Lab<\/a> is a state-of-the art facility providing fast access to information about your specific cancer. The genomic testing guides development of advanced treatments that target the precise genetic composition of your cancer. Because speed is essential in cancer treatment, the genomics lab is part of Norton Cancer Institute, saving time that\u2019s lost when working with outside laboratories.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Norton Cancer Institute <a href=\"https:\/\/nortonhealthcare.com\/services-and-conditions\/cancer-care\/patient-resources\/patient-navigators\/\">patient navigators<\/a> help ease stress and offer emotional support to patients and families. From the point of a suspicious finding through diagnosis, treatment and survivorship, patient navigators help with emotional support, arranging appointments, connecting with resources and more.<\/p>\n\n\n\t<\/div>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\">What to Expect at Norton Cancer Institute Women\u2019s Cancer Center<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Once you\u2019ve been referred to gynecologic oncology at Norton Cancer Institute with a diagnosis, a member of the team will contact you to make an appointment at <a href=\"https:\/\/nortonhealthcare.com\/location\/specialty-centers\/norton-cancer-institute-womens-cancer-center\/\">Norton Cancer Institute Women\u2019s Cancer Center<\/a> in downtown Louisville. If your records aren\u2019t already in your free <a href=\"https:\/\/nortonhealthcare.com\/patient-resources\/mynortonchart\/\">Norton MyChart<\/a> account, the team will contact the referring physician.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Your appointment will be with the first available physician. You\u2019ll also meet the nurse practitioner, nurse clinician and a patient navigator who will help you through treatment and survival.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At your first appointment, your oncologist will review your records and history, including the symptoms that led to the diagnosis. There will be a pelvic exam and a review of the care plan, including any additional imaging, a date for surgery and the plan for any chemotherapy and immunotherapy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The date for surgery will be within a couple weeks of your first appointment. Depending on your diagnosis, chemotherapy and immunotherapy may start in about a week.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">You\u2019ll have surgery scheduled before you leave your first appointment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Early Stage Ovarian Cancer Treatments<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">At Stage 1, or early stage ovarian cancer, the cancer cells are limited to one or both ovaries and possibly one or both fallopian tubes. Symptoms such as bloating or feeling full after not eating much can be attributed to far less serious conditions.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Treatment for early ovarian cancer starts with surgery to remove as much of the cancer as possible. In some cases when just one ovary is diseased, fertility can be preserved by retaining the healthy ovary and fallopian tube.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Depending on your condition, several types of surgery could be pursued.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><a href=\"https:\/\/nortonhealthcare.com\/services-and-conditions\/obstetrics-and-gynecology\/services\/womens-health\/gynecology\/hysterectomy\/\">Hysterectomy<\/a> (removal of the uterus and cervix) with bilateral salpingo-oophorectomy (removal of both ovaries and fallopian tubes) and omentectomy (removal of a section of peritoneum that connects the stomach to other abdominal organs). Lymph nodes and other tissue samples are taken to be examined for spread of cancer cells.<\/li><li>Unilateral salpingo-oophorectomy removes one ovary and fallopian tube from those who may want to become pregnant at some point. This surgery may not be appropriate in cases where cancer cells are present in both ovaries.<\/li><\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Chemotherapy<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">After surgery, further treatment such as chemotherapy depends on the grade of the tumor or how abnormal the cells appear when examined by a pathologist. Cancer cells that look more like healthy cells and aren\u2019t considered likely to grow fast and spread are considered low grade. The more cancer cells look less like healthy cells and are considered more likely to grow quickly, the higher the grade.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Stage 1, low-grade ovarian cancer typically requires no additional treatment after surgery. Treatment of Stage 1 ovarian cancer with higher grade cancer cells can range from observation after surgery to more aggressive chemotherapy, depending on the stage and grade of the tumor.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Chemotherapy drugs are taken either as a pill or through injection to kill or slow the growth of cancer cells. Some chemotherapy is delivered directly to the peritoneal cavity \u2014 the part of the abdomen that holds internal organs \u2014 either during surgery or after.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">About 92% of patients diagnosed with Stage 1 ovarian cancer live five years and longer after diagnosis. Unfortunately, not enough ovarian cancers are diagnosed at this early stage, because symptoms such as bloating and feeling full without eating much can be attributed to other conditions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Advanced Stage Ovarian Cancer Treatments<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Stage 2, 3 or 4 ovarian cancer, fallopian tube cancer or primary peritoneal cancer describe cancer that has spread to some degree beyond the ovaries or fallopian tubes. About 75% of those with cancer that has spread from the ovaries to nearby organs and tissue such as lymph nodes survive five or more years after diagnosis, according to the American Cancer Society. <a href=\"https:\/\/www.cancer.org\/cancer\/types\/ovarian-cancer\/detection-diagnosis-staging\/survival-rates.html\">Five-year survivability<\/a> of ovarian cancer that has spread to more distant parts of the body such as the lungs or the liver is 31%.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Surgery for advanced stage epithelial ovarian cancer is more aggressive, meaning more tissue is removed than in Stage 1 surgery. The goal of cancer surgery is to remove as much of the cancer as possible.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Advanced ovarian cancer surgery may involve a radical hysterectomy \u2014 removal of the uterus, cervix, ovaries, fallopian tubes, lymph nodes and other tissue in the pelvis and abdomen. The tissue will be examined to determine the various grades of tumor. Low-grade cancer cells more closely resemble healthy cells and are likely to grow more slowly than higher-grade cancer cells.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Chemotherapy<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">&nbsp;Advanced ovarian cancer treatment typically involves more aggressive chemotherapy aimed at killing the cancer cells or slowing their growth. Treatment could include one of the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Intravenous chemotherapy that enters the bloodstream to attack cancer cells<\/li><li>Intraperitoneal chemotherapy delivered directly to the abdomen through a small tube<\/li><li>Chemotherapy combined with targeted therapy with drugs that rob cancer cells of what they need to survive and grow<ul><li>Some target the signals the cells rely on to grow, some stop them from forming blood vessels and some block the hormones the cells need to survive.<\/li><\/ul><ul><li>Some targeted therapies trigger the immune system to attack cancer cells.<\/li><\/ul><ul><li>Some targeted therapies, <a href=\"https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/parp-inhibitor\">PARP inhibitors<\/a>, limit the molecules the cancer cells need to repair DNA damaged by other cancer treatments.<\/li><\/ul><\/li><\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Radiation Therapy<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Because aggressive chemotherapy has proven to be more effective against ovarian cancer, radiation therapy is not commonly pursued. It can be a useful tool, however, to target cancer that has spread or metastasized.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">External beam radiation therapy targets cancer cells with radiation from multiple directions. Each beam on its own won\u2019t damage tissue, but when multiple beams are brought together on a precise location, the energy adds up to enough to kill cancer cells. Using multiple beams allows for precise targeting of diseased tissue, leaving healthy tissue unharmed.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Immunotherapy<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Immunotherapy drugs can be a treatment option for some ovarian cancer patients. Immunotherapy triggers the immune system, which normally fights bacteria and viruses, to target cancer cells. Cancer cells sometimes can trick the immune system into thinking they\u2019re healthy cells. Immunotherapy drugs can unmask cancer cells, exposing them to immune system attacks.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Immunotherapy drugs approved for use in certain advanced ovarian cancer patients include dostarlimab and pembrolizumab.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Hormone Therapy<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Epithelial ovarian cancer rarely responds to hormone therapy. The treatment is used more often to treat tumors that develop in the connective cells \u2014 stromal tissue \u2014 of the ovaries. Ovarian stromal tumors are rare.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Norton Cancer Institute Gynecologic Cancer Clinical Trials<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Ovarian cancer treatment is improving rapidly. 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id=\"h-regional-leader-in-cancer-care\">Regional Leader in Cancer Care<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Norton Healthcare is recognized by U.S News &amp; World Report on its \u201cBest Hospitals\u201d list as No. 1 in the Louisville area, with \u201chigh performing\u201d ratings in gynecologic cancer surgery and prostate cancer surgery through Norton Cancer Institute.<\/li>\n\n\n\n<li><strong>First in the world<\/strong>\u00a0to treat a patient with a novel combination therapy for newly diagnosed acute leukemia<\/li>\n\n\n\n<li><strong>First in the world<\/strong>\u00a0to treat a solid tumor patient with ONC-841, a novel immunotherapy drug targeting the SIGLEC-10 immune checkpoint molecule<\/li>\n\n\n\n<li>Recognized for\u00a0<strong>adult oncology<\/strong>\u00a0by\u00a0<strong>Becker\u2019s Hospital Review<\/strong>\u00a0in its \u201c100 Hospitals and Health Systems with Great Oncology Programs\u201d list for 2025<\/li>\n\n\n\n<li><strong>Access to over\u00a0<\/strong><a href=\"https:\/\/nortonhealthcare.com\/services-and-conditions\/cancer-care\/services\/current-cancer-clinical-trials\/\"><strong>170 clinical trials<\/strong><\/a>, offering local patients the\u00a0<strong>same leading-edge options<\/strong>\u00a0available at top national centers<\/li>\n\n\n\n<li><strong>Nationally recognized<\/strong>\u00a0center for early phase research, with\u00a0<strong>23 active Phase 1 clinical trials<\/strong>\u00a0underway<\/li>\n\n\n\n<li><strong>Patients from ore than 20 U.S. states and two foreign countries<\/strong>\u00a0have chosen Norton Cancer Institute for innovative cancer care<\/li>\n\n\n\n<li><strong>Only in Kentucky<\/strong>: Home to the state-of-the-art\u00a0<a href=\"https:\/\/nortonhealthcare.com\/news\/on-site-genomic-testing-at-norton-cancer-institute-allows-fast-and-precise-treatment\/\">Norton Cancer Institute Genomics Lab<\/a>, with support from the Norton Healthcare Foundation and Steven Vanover Foundation, enabling highly precise, genetically targeted cancer therapies<\/li>\n\n\n\n<li><strong>Gamma Tile Center of Excellence,<\/strong>\u00a0as well as a\u00a0<strong>two-time Novalis certification<\/strong>\u00a0for setting the standard for stereotactic radiation<\/li>\n\n\n\n<li><strong>Subspecialized, board-certified\u00a0<\/strong><a href=\"https:\/\/nortonhealthcare.com\/services-and-conditions\/cancer-care\/specialists\/\"><strong>oncologists<\/strong><\/a>\u00a0leading cancer research and treatment advancements<\/li>\n\n\n\n<li><strong>Same-day or next-day appointments<\/strong>\u00a0for newly diagnosed patients, plus\u00a0<a href=\"https:\/\/nortonhealthcare.com\/services-and-conditions\/cancer-care\/locations\/\"><strong>multiple locations<\/strong><\/a>\u00a0and\u00a0<strong>valet parking<\/strong>\u00a0to facilitate access to care<\/li>\n\n\n\n<li><strong>Multidisciplinary clinics<\/strong>\u00a0to provide same-day, same-location access to multiple specialists for more\u00a0<strong>convenient, coordinated care<\/strong><\/li>\n\n\n\n<li><strong>Fully accredited<\/strong>\u00a0by the American College of Surgeons Commission on Cancer, the National Accreditation Program for Breast Centers and the American College of Radiology<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"h-care-designed-with-you-in-mind\">Care Designed With You in Mind<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Comprehensive patient support,\u00a0<\/strong>with five Norton Cancer Institute Resource Center locations throughout Louisville and Southern Indiana, a patient navigator program,\u00a0Norton Cancer Institute\u00a0<a href=\"https:\/\/nortonhealthcare.com\/services-and-conditions\/cancer-care\/patient-resources\/behavioral-oncolology\/\">Behavioral Oncology Program<\/a>, Norton\u00a0<a href=\"https:\/\/nortonhealthcare.com\/services-and-conditions\/palliative-care\/\">Palliative Care Program<\/a>, classes and events, art and music therapy, genetic counseling, nutrition services, financial counseling,\u00a0<a href=\"https:\/\/nortonhealthcare.com\/patient-resources\/pastoral-care\/\">pastoral care<\/a> and more<\/li>\n\n\n\n<li><strong>Medicare, Medicaid and most major insurances accepted<\/strong>, ensuring broad access to care<\/li>\n\n\n\n<li><a href=\"https:\/\/nortonhealthcare.com\/locations\/specialty-pharmacy\/\"><strong>Specialty pharmacy services<\/strong><\/a>\u00a0offer timely, accurate prescriptions with direct pharmacist-to-provider collaboration<\/li>\n\n\n\n<li><strong>24\/7 access to care tools<\/strong>\u00a0via\u00a0<a href=\"https:\/\/nortonhealthcare.com\/patient-resources\/mynortonchart\/\">Norton MyChart<\/a>\u00a0\u2014 message providers, manage appointments, refill prescriptions and more<\/li>\n\n\n\n<li><strong>The\u00a0<\/strong><a href=\"https:\/\/nortonhealthcare.com\/ways-to-help\/norton-healthcare-foundation\/\"><strong>Norton Healthcare Foundation<\/strong><\/a>, the philanthropic arm of Norton Healthcare\u2019s not-for-profit adult-care services, continuously supporting the purchase of new equipment, programs, education and funding of research to ensure our patients stay up to date with medical advances and technology<\/li>\n<\/ul>\n\n\n\t<\/div>\n<\/div>\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h2 class=\"wp-block-heading mt-5\" id=\"h-awards-and-accreditations\">Awards and Accreditations<\/h2>\n\n\n<div class=\"wp-bootstrap-blocks-row row my-5 justify-content-center align-items-center\">\n\t\n\n<div class=\"col-6 col-lg-2 offset-lg-1\">\n\t\t\t\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"200\" src=\"https:\/\/nortonhealthcare.com\/wp-content\/uploads\/2022\/05\/radonc-gold-seal-print.png?wsr\" alt=\"\" class=\"wp-image-1164325\" 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src=\"https:\/\/nortonhealthcare.com\/wp-content\/uploads\/2022\/05\/usnwr-gyn-cancer-badge-2025-26.png?wsr\" alt=\"\" class=\"wp-image-1169635\" srcset=\"https:\/\/nortonhealthcare.com\/wp-content\/uploads\/2022\/05\/usnwr-gyn-cancer-badge-2025-26.png 200w, https:\/\/nortonhealthcare.com\/wp-content\/uploads\/2022\/05\/usnwr-gyn-cancer-badge-2025-26-143x150.png 143w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/figure>\n<\/div>\n\t<\/div>\n\n\n\n<div class=\"col-6 col-lg-2\">\n\t\t\t\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"208\" src=\"https:\/\/nortonhealthcare.com\/wp-content\/uploads\/2022\/05\/usnwr-prostate-cancer-badge-2025-26.png?wsr\" alt=\"\" class=\"wp-image-1169636\" srcset=\"https:\/\/nortonhealthcare.com\/wp-content\/uploads\/2022\/05\/usnwr-prostate-cancer-badge-2025-26.png 200w, 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