{"id":29590,"date":"2019-04-12T15:10:40","date_gmt":"2019-04-12T15:10:40","guid":{"rendered":"http:\/\/nortonhealthcaretest1.flywheelsites.com\/?page_id=232"},"modified":"2025-05-12T12:27:46","modified_gmt":"2025-05-12T16:27:46","slug":"clinical-trials","status":"publish","type":"service","link":"https:\/\/nortonhealthcare.com\/services-and-conditions\/cancer-care\/services\/head-and-neck\/clinical-trials\/","title":{"rendered":"Head and Neck Cancer Clinical Trials"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Norton Cancer Institute physicians lead head and neck cancer clinical trials and studies and publish the results of their discoveries in medical journals, advancing the standard of cancer care.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Their work means that when new treatments are approved for broad use, often Norton Cancer Institute physicians already have years of experience with the therapy. Patients who want to take part in clinical trials can be candidates to access new and innovative treatments.<\/p>\n\n\n\n<div style=\"height:11px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-bootstrap-blocks-row row\">\n\t\n\n<div class=\"col-12 col-xl-6\">\n\t\t\t\n\n<script>\nvar trialH2 = 'Current Head and Neck Cancer Clinical Trials and Studies';\nvar catVar = 'xxx';\nvar emailVar = 'HeadNeck';\nvar contentVar = 'Head and Neck';\nvar contentVar2 = 'Head & Neck';\nvar contentVar3 = 'Oropharyngeal';\nvar titleVar = 'xxx';\nvar drugVar = 'xxx';\nvar piVar = 'xxx';\n<\/script>\n\n\n\n<style>\n.ctstyle_img {\n     width:75px;\n     display:inline-block;\n     margin-right: 5px;\n     margin-top:5px;\n     margin-bottom:5px;\n}\n\n.ctstyle_combo {\n     vertical-align:middle;\n     display: inline-block;\n     font-size:small;\n}\n\n.ct_icon  {\n     margin-right:5px;\n}\n<\/style>\n\n<script>\ndocument.addEventListener('DOMContentLoaded', function() {\n  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(resultsFound > 0) {\n                document.getElementById(\"trialsContainer\").style.display = \"block\";\n                document.getElementById(\"trialsHeading\").innerHTML = trialH2;\n                document.getElementById(\"trials\").innerHTML = trialsHtml;\n                document.getElementById(\"trials2\").innerHTML = trials2Html;\n            } else {\n                document.getElementById(\"trialsContainer\").style.display = \"none\";\n            }\n        })\n        .catch(error => {\n            console.error('Error fetching data:', error);\n        });\n});\n<\/script>\n\n<!-- Container for all trial results -->\n<div id=\"trialsContainer\" style=\"display: none;\">\n    <!-- Heading that will be populated with trialH2 -->\n    <h2 id=\"trialsHeading\"><\/h2>\n    <!-- Trial results containers -->\n    <div id=\"trials\"><\/div>\n    <div id=\"trials2\"><\/div>\n<\/div>\n\n\t<\/div>\n\n\n\n<div class=\"col-12 col-xl-6\">\n\t\t\t\n\n<h2 class=\"wp-block-heading\" id=\"h-recently-published-head-and-neck-cancer-research-from-norton-cancer-institute-physicians\">Recently Published Head and Neck Cancer Research from Norton Cancer Institute Physicians<\/h2>\n\n\n\n<style>\nli.wp-block-rss__item {\nmargin-bottom:20px;\n}\n<\/style>\n\n\n<ul class=\"wp-block-rss\"><li class='wp-block-rss__item'><div class='wp-block-rss__item-title'><a href='https:\/\/pubmed.ncbi.nlm.nih.gov\/40523897\/?utm_source=WordPress&#038;utm_medium=rss&#038;utm_campaign=pubmed-2&#038;utm_content=1jeAVjyuKpXdEVXUZHLaKQeGkXSvAwkyNxlBZ7lVy0h6gffEgQ&#038;fc=20230320175807&#038;ff=20260623224820&#038;v=2.20.0'>Garsorasib, a KRAS G12C inhibitor, with or without cetuximab, an EGFR antibody, in colorectal cancer cohorts of a phase II trial in advanced solid tumors with KRAS G12C mutation<\/a><\/div><\/li><li class='wp-block-rss__item'><div class='wp-block-rss__item-title'><a href='https:\/\/pubmed.ncbi.nlm.nih.gov\/40125219\/?utm_source=WordPress&#038;utm_medium=rss&#038;utm_campaign=pubmed-2&#038;utm_content=1jeAVjyuKpXdEVXUZHLaKQeGkXSvAwkyNxlBZ7lVy0h6gffEgQ&#038;fc=20230320175807&#038;ff=20260623224820&#038;v=2.20.0'>Initial Endoscopic Ventricular Failure to Relieve Hydrocephalus in Patients With Obstructing Brain Tumors Predicts a Histone 3K27M Mutation<\/a><\/div><\/li><li class='wp-block-rss__item'><div class='wp-block-rss__item-title'><a href='https:\/\/pubmed.ncbi.nlm.nih.gov\/39974223\/?utm_source=WordPress&#038;utm_medium=rss&#038;utm_campaign=pubmed-2&#038;utm_content=1jeAVjyuKpXdEVXUZHLaKQeGkXSvAwkyNxlBZ7lVy0h6gffEgQ&#038;fc=20230320175807&#038;ff=20260623224820&#038;v=2.20.0'>Ventriculoperitoneal Shunt and Endoscopic Third Ventriculostomy for Hydrocephalus in Adult Patients With Brain Metastases<\/a><\/div><\/li><li class='wp-block-rss__item'><div class='wp-block-rss__item-title'><a href='https:\/\/pubmed.ncbi.nlm.nih.gov\/39601195\/?utm_source=WordPress&#038;utm_medium=rss&#038;utm_campaign=pubmed-2&#038;utm_content=1jeAVjyuKpXdEVXUZHLaKQeGkXSvAwkyNxlBZ7lVy0h6gffEgQ&#038;fc=20230320175807&#038;ff=20260623224820&#038;v=2.20.0'>HPV-Associated Head and Neck Second Primary Tumors-A Case Series<\/a><\/div><\/li><li class='wp-block-rss__item'><div class='wp-block-rss__item-title'><a href='https:\/\/pubmed.ncbi.nlm.nih.gov\/39097413\/?utm_source=WordPress&#038;utm_medium=rss&#038;utm_campaign=pubmed-2&#038;utm_content=1jeAVjyuKpXdEVXUZHLaKQeGkXSvAwkyNxlBZ7lVy0h6gffEgQ&#038;fc=20230320175807&#038;ff=20260623224820&#038;v=2.20.0'>Phase I studies of davoceticept (ALPN-202), a PD-L1-dependent CD28 co-stimulator and dual PD-L1\/CTLA-4 inhibitor, as monotherapy and in combination with pembrolizumab in advanced solid tumors (NEON-1 and NEON-2)<\/a><\/div><\/li><\/ul>\n\n<div class=\"wp-bootstrap-blocks-button\">\n\t<a\n\t\thref=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=%28%28spalding%2C+a%5BAuthor%5D+OR+grewal+j%5BAuthor%5D+OR+jung+j%5BAuthor%5D+OR+hahl%2C+m%5BAuthor%5D+OR+little+j%5BAuthor%5D+OR+tennant%5BAuthor%5D%29+AND+%22Norton+Cancer%22%5BAffiliation%5D%29+OR+%28%22Head+and+Neck+Neoplasms%22%5BMeSH+Terms%5D+AND+%22Norton+Cancer%22%5BAffiliation%5D%29&#038;sort=date\"\n\t\t\t\t\ttarget=\"_blank\"\n\t\t\t\t\t\t\trel=\"noreferrer noopener\"\n\t\t\t\tclass=\"btn btn-primary\"\n\t>\n\t\tRead More at Pubmed.gov\t<\/a>\n<\/div>\n\n\t<\/div>\n\n<\/div>\n\n\n\n\n<div class=\"card card-callout    \">\n\t<div class=\"card-body\">\n\t\t\n\n<h2 class=\"wp-block-heading has-text-align-center\" id=\"h-norton-cancer-institute\">Norton Cancer Institute<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"h-regional-leader-in-cancer-care\">Regional Leader in Cancer Care<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Norton Healthcare is recognized by U.S News &amp; World Report on its \u201cBest Hospitals\u201d list as No. 1 in the Louisville area, with \u201chigh performing\u201d ratings in gynecologic cancer surgery and prostate cancer surgery through Norton Cancer Institute.<\/li>\n\n\n\n<li><strong>First in the world<\/strong>\u00a0to treat a patient with a novel combination therapy for newly diagnosed acute leukemia<\/li>\n\n\n\n<li><strong>First in the world<\/strong>\u00a0to treat a solid tumor patient with ONC-841, a novel immunotherapy drug targeting the SIGLEC-10 immune checkpoint molecule<\/li>\n\n\n\n<li>Recognized for\u00a0<strong>adult oncology<\/strong>\u00a0by\u00a0<strong>Becker\u2019s Hospital Review<\/strong>\u00a0in its \u201c100 Hospitals and Health Systems with Great Oncology Programs\u201d list for 2025<\/li>\n\n\n\n<li><strong>Access to over\u00a0<\/strong><a href=\"https:\/\/nortonhealthcare.com\/services-and-conditions\/cancer-care\/services\/current-cancer-clinical-trials\/\"><strong>170 clinical trials<\/strong><\/a>, offering local patients the\u00a0<strong>same leading-edge options<\/strong>\u00a0available at top national centers<\/li>\n\n\n\n<li><strong>Nationally recognized<\/strong>\u00a0center for early phase research, with\u00a0<strong>23 active Phase 1 clinical trials<\/strong>\u00a0underway<\/li>\n\n\n\n<li><strong>Patients from ore than 20 U.S. states and two foreign countries<\/strong>\u00a0have chosen Norton Cancer Institute for innovative cancer care<\/li>\n\n\n\n<li><strong>Only in Kentucky<\/strong>: Home to the state-of-the-art\u00a0<a href=\"https:\/\/nortonhealthcare.com\/news\/on-site-genomic-testing-at-norton-cancer-institute-allows-fast-and-precise-treatment\/\">Norton Cancer Institute Genomics Lab<\/a>, with support from the Norton Healthcare Foundation and Steven Vanover Foundation, enabling highly precise, genetically targeted cancer therapies<\/li>\n\n\n\n<li><strong>Gamma Tile Center of Excellence,<\/strong>\u00a0as well as a\u00a0<strong>two-time Novalis certification<\/strong>\u00a0for setting the standard for stereotactic radiation<\/li>\n\n\n\n<li><strong>Subspecialized, board-certified\u00a0<\/strong><a href=\"https:\/\/nortonhealthcare.com\/services-and-conditions\/cancer-care\/specialists\/\"><strong>oncologists<\/strong><\/a>\u00a0leading cancer research and treatment advancements<\/li>\n\n\n\n<li><strong>Same-day or next-day appointments<\/strong>\u00a0for newly diagnosed patients, plus\u00a0<a href=\"https:\/\/nortonhealthcare.com\/services-and-conditions\/cancer-care\/locations\/\"><strong>multiple locations<\/strong><\/a>\u00a0and\u00a0<strong>valet parking<\/strong>\u00a0to facilitate access to care<\/li>\n\n\n\n<li><strong>Multidisciplinary clinics<\/strong>\u00a0to provide same-day, same-location access to multiple specialists for more\u00a0<strong>convenient, coordinated care<\/strong><\/li>\n\n\n\n<li><strong>Fully accredited<\/strong>\u00a0by the American College of Surgeons Commission on Cancer, the National Accreditation Program for Breast Centers and the American College of Radiology<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"h-care-designed-with-you-in-mind\">Care Designed With You in Mind<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Comprehensive patient support,\u00a0<\/strong>with five Norton Cancer Institute Resource Center locations throughout Louisville and Southern Indiana, a patient navigator program,\u00a0Norton Cancer Institute\u00a0<a href=\"https:\/\/nortonhealthcare.com\/services-and-conditions\/cancer-care\/patient-resources\/behavioral-oncolology\/\">Behavioral Oncology Program<\/a>, Norton\u00a0<a href=\"https:\/\/nortonhealthcare.com\/services-and-conditions\/palliative-care\/\">Palliative Care Program<\/a>, classes and events, art and music therapy, genetic counseling, nutrition services, financial counseling,\u00a0<a href=\"https:\/\/nortonhealthcare.com\/patient-resources\/pastoral-care\/\">pastoral care<\/a> and more<\/li>\n\n\n\n<li><strong>Medicare, Medicaid and most major insurances accepted<\/strong>, ensuring broad access to care<\/li>\n\n\n\n<li><a href=\"https:\/\/nortonhealthcare.com\/locations\/specialty-pharmacy\/\"><strong>Specialty pharmacy services<\/strong><\/a>\u00a0offer timely, accurate prescriptions with direct pharmacist-to-provider collaboration<\/li>\n\n\n\n<li><strong>24\/7 access to care tools<\/strong>\u00a0via\u00a0<a href=\"https:\/\/nortonhealthcare.com\/patient-resources\/mynortonchart\/\">Norton MyChart<\/a>\u00a0\u2014 message providers, manage appointments, refill prescriptions and more<\/li>\n\n\n\n<li><strong>The\u00a0<\/strong><a href=\"https:\/\/nortonhealthcare.com\/ways-to-help\/norton-healthcare-foundation\/\"><strong>Norton Healthcare Foundation<\/strong><\/a>, the philanthropic arm of Norton Healthcare\u2019s not-for-profit adult-care services, continuously supporting the purchase of new equipment, programs, education and funding of research to ensure our patients stay up to date with medical advances and technology<\/li>\n<\/ul>\n\n\n\t<\/div>\n<\/div>\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<h2 class=\"wp-block-heading mt-5\" id=\"h-awards-and-accreditations\">Awards and Accreditations<\/h2>\n\n\n<div class=\"wp-bootstrap-blocks-row row my-5 justify-content-center align-items-center\">\n\t\n\n<div class=\"col-6 col-lg-2 offset-lg-1\">\n\t\t\t\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"200\" src=\"https:\/\/nortonhealthcare.com\/wp-content\/uploads\/2022\/05\/radonc-gold-seal-print.png?wsr\" alt=\"\" class=\"wp-image-1164325\" srcset=\"https:\/\/nortonhealthcare.com\/wp-content\/uploads\/2022\/05\/radonc-gold-seal-print.png 200w, https:\/\/nortonhealthcare.com\/wp-content\/uploads\/2022\/05\/radonc-gold-seal-print-150x150.png 150w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/figure>\n<\/div>\n\t<\/div>\n\n\n\n<div class=\"col-6 col-lg-2\">\n\t\t\t\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" src=\"https:\/\/urldefense.com\/v3\/__https:\/\/nortonhealthcare.com\/wp-content\/uploads\/qp_commisiononcancer_accredprog.png__;!!JJ2OXQNEuZvuoA!oRYu1UmvlNYp_ZzGYhCahGF_87oWxc7MJV4ajPeTUvAUSARZB7JjSYA1Jlg5KEkXA0AlcZvHqzOPywLd2vKdptT0Eb2NrvUsviWg$\" alt=\"\"\/><\/figure>\n<\/div>\n\t<\/div>\n\n\n\n<div class=\"col-6 col-lg-2\">\n\t\t\t\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" src=\"https:\/\/urldefense.com\/v3\/__https:\/\/nortonhealthcare.com\/wp-content\/uploads\/napbc.png__;!!JJ2OXQNEuZvuoA!oRYu1UmvlNYp_ZzGYhCahGF_87oWxc7MJV4ajPeTUvAUSARZB7JjSYA1Jlg5KEkXA0AlcZvHqzOPywLd2vKdptT0Eb2NruoHIzb2$\" alt=\"\"\/><\/figure>\n<\/div>\n\t<\/div>\n\n\n\n<div class=\"col-6 col-lg-2\">\n\t\t\t\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" src=\"https:\/\/nortonhealthcare.com\/wp-content\/uploads\/GO2-Care-Continuum-Logo.png\" alt=\"\"\/><\/figure>\n<\/div>\n\t<\/div>\n\n\n\n<div class=\"col-6 col-lg-2\">\n\t\t\t\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" src=\"https:\/\/nortonhealthcare.com\/wp-content\/uploads\/GO2-Screening-Logo.png\" alt=\"\"\/><\/figure>\n<\/div>\n\t<\/div>\n\n\n\n<div class=\"col-6 col-lg-2\">\n\t\t\t\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"210\" src=\"https:\/\/nortonhealthcare.com\/wp-content\/uploads\/2022\/05\/usnwr-gyn-cancer-badge-2025-26.png?wsr\" alt=\"\" class=\"wp-image-1169635\" srcset=\"https:\/\/nortonhealthcare.com\/wp-content\/uploads\/2022\/05\/usnwr-gyn-cancer-badge-2025-26.png 200w, https:\/\/nortonhealthcare.com\/wp-content\/uploads\/2022\/05\/usnwr-gyn-cancer-badge-2025-26-143x150.png 143w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/figure>\n<\/div>\n\t<\/div>\n\n\n\n<div class=\"col-6 col-lg-2\">\n\t\t\t\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"208\" src=\"https:\/\/nortonhealthcare.com\/wp-content\/uploads\/2022\/05\/usnwr-prostate-cancer-badge-2025-26.png?wsr\" alt=\"\" class=\"wp-image-1169636\" srcset=\"https:\/\/nortonhealthcare.com\/wp-content\/uploads\/2022\/05\/usnwr-prostate-cancer-badge-2025-26.png 200w, https:\/\/nortonhealthcare.com\/wp-content\/uploads\/2022\/05\/usnwr-prostate-cancer-badge-2025-26-144x150.png 144w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/figure>\n<\/div>\n\t<\/div>\n\n<\/div>\n<\/div><\/div>\n","protected":false},"featured_media":1128068,"parent":230,"menu_order":2,"template":"","class_list":["post-29590","service","type-service","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.9 (Yoast SEO v27.9) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Head and Neck Cancer Clinical Trials | Norton Healthcare<\/title>\n<meta name=\"description\" content=\"Norton Cancer Institute physicians lead head and neck cancer clinical trials and studies and publish the results of their discoveries in medical journals, advancing the standard of cancer care.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nortonhealthcare.com\/services-and-conditions\/cancer-care\/services\/head-and-neck\/clinical-trials\/\" 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